In 2004, a group led by Mikhail Kolonin from the M.D. Anderson Cancer Center (Houston, Texas) published a paper in Nature Medicine that seemed almost like science fiction at the time: a peptide capable of selectively destroying the blood vessels that supply adipose tissue. Mice lost up to 30% of their fat mass over four…

In the world of peptide bio-regulators, some molecules have remained in the shadow of “high-profile” compounds like BPC-157 or semaglutide for decades – yet they are no less scientifically interesting. One such molecule is pinealon. If you’re wondering what is the pinealon peptide, the answer sounds deceptively simple: it is a tripeptide consisting of just…