-
Bioregulator Peptides as a Class: The Khavinson Research Tradition

Bioregulator peptides are short-chain compounds (typically two to four amino acids) derived from or modeled on sequences found in specific organ tissues. The research hypothesis behind them is that these sequences carry tissue-specific regulatory information: that a peptide extracted from thymus tissue, for instance, carries signals relevant to immune cell function that a synthetic analog…
-
The Ghrelin System: Why GH Secretagogue Peptides Target GHSR

Walk through enough peptide research literature, and one receptor keeps showing up – GHSR, the growth hormone secretagogue receptor. It’s the binding site for ghrelin, it controls one of the most important pulsatile hormone systems in the body, and it’s become a central target for researchers studying recovery, body composition, and age-related hormonal decline. The…
-
The AMPK Signaling Pathway: Research Context for MOTS-C and SLU-PP-332

Metabolic research in recent years has shifted the focus from end-point phenotypic measures – such as body weight and glucose levels – to a more fundamental question: what regulates energy balance at the single-cell level? The answer to this question increasingly points to a single molecular hub: AMPK, the AMP-activated protein kinase. It is precisely…