GHK-Cu 50mg

GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine, a naturally occurring peptide prominent in human biological fluids. The peptide has a uniquely high affinity for copper ions, forming a stable chelate with copper(II) that is more exchangeable than the copper bound to albumin, allowing efficient copper delivery to tissues. GHK-Cu plays an important role in tissue regeneration, wound healing, and skin remodeling through multiple mechanisms: it promotes the recruitment and activation of repair cells, enhances the synthesis of extracellular matrix components (including collagen, elastin, and glycosaminoglycans), modulates extracellular matrix turnover by increasing both metalloproteinases and their inhibitors, and exhibits powerful anti-inflammatory and antioxidant effects. GHK-Cu additionally downregulates scar formation and fibrotic processes, suppresses harmful cytokines and signal transduction pathways (such as TGF-?1/Smad), and supports angiogenesis and stem cell differentiation. Preclinical and clinical studies demonstrate its efficacy in accelerating lesion repair in skin, bone, and internal organs, as well as reducing the impact of oxidative stress and chronic inflammation. Owing to its broad and potent activity profile and high safety margin in mammals, GHK-Cu is a valuable tool for studying tissue repair, regenerative biology, age-related degeneration, and as a model therapeutic agent in peptide research^1,2,4.